Blood Group Systems
The term Blood Group refers to the individual's Red cell surface antigens. These antigens are mainly Glycoproteins or glycolipids that form in RBC membranes. The International Society of Blood Transfusion (ISBT) working Party for Red Cell immunogenetics groups has maintained the records of RBC antigens as follows:
1. Blood Group Systems
2. Collections (201 Series)
3. Low prevalence Antigens (700 Series)
4. High Prevalence Antigens (901 Series)
1. Blood Group Systems:
Blood group systems are defined as systems of one or more antigens governed by a single gene or complex of two or more closely linked homologous genes. In order for a blood group system and its antigens to be recognized the underlying genetic variation must be identified, sequenced, and confirmed to affect phenotype. Currently, 44 recognized Blood Group systems containing 354 antigens are discovered. The 44 Blood Group Systems are genetically determined by 49 genes.
2. Collection: (201 series)
Designed to group biochemically, genetically, or serologically similar antigens where the genetic basis has not yet been discovered.
3. 700 series :
The 700 series contains antigens that do not fit in any system or collection which have an incidence of <1% across all human Ethnic population. It is also known as low prevalence antigens.
4. 901 Series :
The 901 series contains high-incidence antigens with an incidence of >90% and cannot be included in system or collection.
https://www.isbtweb.org/resource/tableofhighincidenceantigens901series.html
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