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Can
Diabetic Donors Donate Blood?
About Blood donation for Diabetes mellitus, the recent guidelines say that the person requiring insulin and/or complications of diabetes with multi-organ failure is NOT eligible for the donation of blood. The person will be ACCEPTED for donation if the Diabetes Mellitus is controlled by diet or Oral hypoglycemic medications with no history of Ortho-stastic hypotension and No evidence of Infection, neuropathy or vascular diseases. Again, the person taking oral hypoglycemic medication has NOT been accepted if the medication is altered or the dosage of medication is adjusted in the last 4 weeks.
Blood
Donation and Glycemic Control:
The glycaemic status of the donor can be improved even after a single blood donation. The improvement was particularly evident three weeks after donation. Giving blood removes some iron from the body, perhaps helping restore insulin signaling. Blood donation could be an alternative way to improve glycaemic status, particularly in people with impaired glucose tolerance who are on a diet and have not started their treatment yet. It is well known that low iron stores may contribute to enhance insulin sensitivity. Iron-containing compounds in the blood can produce damaging molecules, known as reactive oxygen species, which have been shown to interfere with insulin signaling. (Borai et. al)
The Glycosylated Hemoglobine (HBA1c) dropped significantly after whole blood donation in more than half of the blood donors. On Comparison to the relative maximum reduction, the Author found no significant difference between Diabetics and Non-Diabetes donors. They recommend that Type-2 diabetes patients who donate blood should have at least 4 months interval between blood donation and measurement of HBA1c should be performed at the end of 4 months interval (Dijkstra A et.al).
In another study Fernadez-Real JM et.al observed a mean decrease of HbA1c by approximately 15% (SI UNITS) in high-ferritin Type-2 Diabetic donors.
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