Want To Donate Blood. Can I? Can Diabetic Donors Donate Blood? About Blood donation for Diabetes mellitus, the recent guidelines say that the person requiring insulin and/or complications of diabetes with multi-organ failure is NOT eligible for the donation of blood. The person will be ACCEPTED for donation if the Diabetes Mellitus is controlled by diet or Oral hypoglycemic medications with no history of Ortho-stastic hypotension and No evidence of Infection, neuropathy or vascular diseases. Again, the person taking oral hypoglycemic medication has NOT been accepted if the medication is altered or the dosage of medication is adjusted in the last 4 weeks. Blood Donation and Glycemic Control: The glycaemic status of the donor can be improved even after a single blood donation. The improvement was particularly evident three weeks after donation. Giving blood removes some iron from the body, perhaps helping restore insulin signaling. Blood donation could be an alter